There are essential nutrients and vitamins needed for bone support. Calcium and magnesium are two minerals known to be essential for bone health. Vitamin D-3 and vitamin K-2 are fat soluble vitamins. Vitamin D3 has been shown to play a critical role in bone metabolism, as well as in the absorption of calcium and magnesium in the intestine. Whereas vitamin K-2 further supports bone health through its participation in healthy bone calcification.†
Magnesium is an essential mineral that is a required cofactor for well over 300 chemical reactions in the body. In all, magnesium takes part in more chemical reactions than any other nutrient. The benefits of magnesium are also great and important for a healthy body. Roughly half of magnesium is found in the bones while the other portion is inside the body tissue and organ cells. Magnesium helps to maintain a normal function of muscles and nerves as well as a steady heart rhythm, a healthy immune system and keeping bones strong. 
Some good sources include (but not limited to):
- Potato with skin
- Leafy green vegetables,
- Whole grains,
According to the most recent U.S. Dietary Guidelines, there are seven important nutrients in food that most Americans aren't getting in sufficient amounts. Amongst those include the essential mineral magnesium (WebMD). Unfortunately, the typical U.S. diet is lacking in the essential mineral magnesium. Most people do not consume even the minimum recommended daily value of this important nutrient. For some individuals, higher amounts of magnesium are required due to increased activity levels/energy requirements, presence of chronic disease, etc.
Magnesium deficiency (aka hypomagnesemia) or inadequacy can result from excess consumption of alcohol, a side effect of certain medications, and some health conditions, including gastrointestinal disorder and diabetes. Deficiency is more common in older adults.
Symptoms of magnesium deficiency include:
- a loss of appetite
- nausea or vomiting
- fatigue or weakness
Symptoms of more advanced magnesium deficiency include:
- muscle cramps
- personality changes
- heart rhythm changes or spasms
Research has linked magnesium deficiency with a range of health conditions, including Alzheimer’s disease, type 2 diabetes, cardiovascular disease, and migraine.
An overdose of magnesium through dietary sources is unlikely because the body will eliminate any excess magnesium from food through urine. However, a high intake of magnesium from supplements can lead to gastrointestinal problems, such as diarrhea, nausea, or cramping. 
Calcium is a nutrient that all living organisms need, including humans. It is the most abundant mineral in the body, and it is vital for bone health.Humans need calcium to build and maintain strong bones, and 99% of the body’s calcium is in the bones and teeth. It is also necessary for maintaining healthy communication between the brain and other parts of the body. It plays a role in muscle movement and cardiovascular function.
Some good sources include (but not limited to):
- fortified dairy alternatives, such as soy milk
- sardines and salmon
- nuts and seeds, especially almonds, sesame, and chia
- legumes and grains
- green leafy vegetables, such as broccoli, turnip leaves, watercress, and kale
Some dark green vegetables, such as spinach, contain calcium. However, they also contain high levels of oxalic acid. Oxalic acid reduces the body’s ability to absorb calcium, according to studies.
Some causes of Calcium deficiency but not limited to include:
- bulimia, anorexia, and some other eating disorders.
- overconsumption of magnesium
- long-term use of laxatives
- prolonged use of some medicines, such as chemotherapy or corticosteroids
- people who eat a lot of protein or sodium may excrete calcium.
- some cancers
- high consumption of caffeine, soda, or alcohol
- some conditions, such as celiac disease, inflammatory bowel disease, Crohn’s disease, and some other digestive diseases
- some surgical procedures, including removing the stomach
- kidney failure
- vitamin D deficiency
- phosphate deficiency
The body eliminates some calcium in sweat, urine, and feces. Foods and activities that encourage these functions may reduce the levels of calcium in the body.
Vitamin D is a fat-soluble vitamin that can be ingested by foods such as fatty fish, dairy products, and eggs, but is mainly synthesized by the human skin when exposed to sunlight. Vitamin D plays a main role in regulating calcium metabolism by increasing intestinal calcium absorption
Vitamin D deficiency is reaching epidemic proportions. Why? Because many people have limited exposure to sunlight (the body’s natural way to make vitamin D) or wear sunscreens; as we age our bodies make less vitamin D; and people who take statin medications, people with digestive issues such as Crohn’s or celiac disease, vegetarians or people suffering from obesity are also at risk for deficiency. 
Vitamin K is another fat-soluble vitamin that exists in two forms of vitamin K. vitamin K1 (phylloquinone) is mainly found in green leafy vegetables which are unfortunately not typically consumed in high enough amounts. Vitamin K2 (menaquinone) is mainly found in fermented dairy and produced by lactic acid bacteria in the intestine (ie: vitamin K2 is manufactured by your friendly intestinal flora). However, Vitamin K2 production may be hampered by poor digestion. The role of vitamin K in cardiovascular health has mainly been studied in isolation; however, a growing body of evidence suggests a synergistic effect of vitamin K combined with vitamin D. 
Boron is a mineral that is found in food such as nuts and the environment.
Boron seems to affect the way the body handles other minerals such as calcium, magnesium, and phosphorus. It also seems to increase estrogen levels in older (post-menopausal) women and healthy men. Estrogen is thought to be helpful in maintaining healthy bones and mental function. 
Unfortunately, nutrient-depleted soil has led to low levels of boron in our food supply. Research shows that low levels of this nutrient have caused joint problems to skyrocket.
Boron is used for boron deficiency, menstrual cramps, and vaginal yeast infections. It is sometimes used for athletic performance, osteoarthritis, weak or brittle bones (osteoporosis), and other conditions.
Dr. Kenawy’s Bone Support formula is a comprehensive, synergistic formulation of essential vitamins and minerals designed to support healthy bone density. His unique formula combines the 3 most important nutrients to keep your heart, bones, and immune health in top-notch form, no matter what your age. All essential to your health however-also nutrients that many people are deficient in-vitamin D, vitamin K and boron (in the form of patented FruiteX-B® calcium fructoborate) result in a comprehensive supplement that supports the 3 most important systems in your body.†
- A comprehensive, synergistic formulation of essential vitamins and minerals designed to support healthy bone density
- L-OptiZinc® (zinc as monomethionine): the only high-potency zinc supplement FDA-approved safe for human nutrition.
- Low dose, fully soluble, and vegan FruiteX-B®(High-Potency, Patented Form of Boron) is a patented mineral complex found in legumes, fruits, vegetables, herbs, and wine. Over a dozen studies show its unique ability to support and maintain joint, bone, and cardiovascular health.
- 25mcg (1000IU) of Vitamin D3 as cholecalciferol)
- 45mcg of Vitamin K-2 to maximize calcium absorption and utilization.
- Bone Health: Vitamin D helps regulate the level of calcium in your blood and helps boost bone density. Vitamin K helps bind osteocalcin –an important bone-building protein—to calcium, so it can be utilized by your bones. Plus, research shows that boron can help prevent bone loss and support bone density.
- Cardiovascular support: Did you know that inflammation in your arteries is one of the leading causes of heart and artery problems? Both Vitamin D and Boron contain compounds that help counteract this inflammation overload. Studies also show that boron helps lower blood levels of C-reactive protein (CRP). High CRP levels are a marker for heart disease.
- Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health
- Immune Health: There is increasing evidence that links low levels of Vitamin D with such autoimmune diseases as Crohn’s, multiple sclerosis, rheumatoid arthritis, diabetes mellitus, inflammatory bowel disease and lupus. Vitamin D and Boron work together to help support healthy inflammatory response and a strong immune system. helps support a healthy immune response.
- Clinically researched, fast-acting and long-lasting joint support: FruiteX-B® is a patented ingredient identical to the borate carbohydrate complex commonly found in legumes, fruits, vegetables and certain beans. FruiteX-B® is supported by over a decade of published research that establishes safety and statistically significant improvement in human joint comfort. In clinical studies, significant improvements have been shown in joint comfort with continued use of FruiteX-B® when studied over a long term 90-day period of time.*
- Studies show that L-OptiZinc® is absorbed better, retained longer and is more effective than ordinary zinc supplements tested, and resists binding with dietary fiber and phytate, organic compounds that inhibit zinc absorption.
†These statements have not been evaluated by The Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Information and statements made are for education purposes and are not intended to replace the advice of your General Practitioner. If you have a severe medical condition or health concern, see your physician.
 WebMD LLC. (2019, September 23). Magnesium and Your Health. WebMD. https://www.webmd.com/diet/magnesium-and-your-health#
 MedicalNewsToday. (2020, January 6). Why do we need magnesium? MedicalNewsToday. https://www.medicalnewstoday.com/articles/286839#risks-of-too-much-magnesium
 MedicalNewsToday. (2020, January 28). Benefits and sources of calcium. https://www.medicalnewstoday.com/articles/248958
 AB, SP, AT, MG, NV. (2017, September 12). The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. National Center for Biotechnology Information, U.S. National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/
 WebMD LLC. (2019). BORON. https://www.webmd.com/vitamins/ai/ingredientmono-894/boron